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THE PREVALENCE OF POLYMORPHISMS OF SOME GENES ASSOCIATED WITH THE FUNCTION OF PLASMA-PLATELET HEMOSTASIS, WITH ASPIRIN RESISTANCE IN THE KAZAKH POPULATION
The relevance of the research topic: Aspirin is the most common antiplatelet drug in world clinical practice. It is a first-line agent in the treatment of acute forms of vascular insufficiency associated with atherosclerosis of the arteries. In addition, along with antihypercholesterol drugs, aspirin is most often used for primary and secondary prevention of these conditions. A rather common condition in a population is a decrease in the effectiveness of aspirin, defined by the term «aspirin resistance». The main cause of aspirin resistance is considered to be the genetic characteristics of pa...
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2018 year | Issue: 5 | Pages: 164-171
NATIONAL EXPERTISE CENTER BRANCHES AND DEPARTMENTS OF PUBLIC HEALTH PROTECTION COMMITTEE SPECIALISTS OPINIONS ABOUT THE ACTIVITIES AND STATUS OF SANITARY AND EPIDEMIOLOGICAL EXPERTISE ORGANIZATION
Background. The Sanitary and Epidemiological Expertise Institutions - the branches of the RSE the National Expertise Center (hereinafter referred to as the NEC) of the Republic of Kazakhstan Ministry of Health, Public Health Protection Committee (hereinafter referred to as the RK MoH, PHPC) execute laboratory research in the field of ensuring the state guarantees to the citizens of the Republic of Kazakhstan for sanitary, epidemiological, ecological well-being and radiation safety [11]. The main customers of laboratory control within the SSES (State Sanitary and Epidemiological Surveillance) a...
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2018 year | Issue: 5 | Pages: 153-163
CONGENITAL HEART DISEASES AND CONNECTIVE TISSUE DYSPLASIA CHILDREN OF SEMEY, THE DETERMINATION THE FREQUENCY
Introduction. The community of pathogenetic mechanisms of congenital heart diseases and connective tissue dysplasia connective tissue dysplasia defines increase in risk of their combinations. At the same time perhaps essential deterioration in the forecast of a current and conditions for correction of connective tissue dysplasia. So far poorly studied are an actual frequency and structure of combinations of these pathological states in population.
Research objective – to determine the frequency of signs connective tissue dysplasia in children with connective tissue dysplasia are living in S...
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2018 year | Issue: 5 | Pages: 145-152
FACTORS OF ADDICTIVE PREDISPOSITION AMONG FIRST-YEAR STUDENTS OF SEMEY STATE MEDICAL UNIVERSITY
Introduction: Training in a medical university is associated with a tense adaptation, which leads to a change in the mental status of students. This may result in vulnerability to addictions and the possible development of dependent behavior.
The aim of the study was to determine the prevalence of the addiction risk in students of the Semey State Medical University of (SSMU), as well as in the context of interrelated socio-psychological factors.
Materials and methods: A one-stage cross-sectional evaluation was carried out using a questionnaire of 643 first-year students of the Semey State Me...
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2018 year | Issue: 5 | Pages: 135-144
PREVALENCE AND SEVERITY OF SOMATIC DISTRESS AND FATIGUE AMONG RESIDENTS OF EAST KAZAKHSTAN REGION EXPOSED TO RADIATION DUE TO THE ACTIVITY OF THE SEMIPALATINSK NUCLEAR TEST SITE
Background: since Kazakhstan belongs to the range of industrialized world nations, most of its territory is affected by anthropogenic and man-induced risk factors, which contribute to the development of unfavorable ecological situation that has negative impact on the population health. Nuclear weapons tests at the Semipalatinsk nuclear test site have caused significant adverse changes in the habitat of hundreds of thousands of people who are now forced to live and conduct economic activities in territories contaminated with radionuclides. Studying the long-term effects of small radiation doses...
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2018 year | Issue: 5 | Pages: 125-134